Christian McCaffrey and the San Francisco 49ers suffered their first loss of the season in their recent matchup against the Jacksonville Jaguars. Before that defeat, the 49ers had been on a smooth three-game winning streak and looked nearly unstoppable.

The 49ers have faced a few challenges this season as injuries have disrupted their rhythm. Quarterback Brock Purdy missed a couple of games but made his return against the Jaguars, where he threw two touchdown passes. Meanwhile, tight end George Kittle, who went down with an injury in the season opener, remains sidelined, and it’s still unclear when he’ll make his comeback to the field.

Christian McCaffrey and the San Francisco 49ers are now set to square off against the Los Angeles Rams on Thursday Night Football. Both the 49ers and Rams currently hold identical records with three victories and a single loss, and each team will be determined to boost their win totals as the season progresses.

The Rams’ offense is led by veteran quarterback Matthew Stafford, who’s hungry for another Super Bowl title this year. Now in his 30s, Stafford is pushing hard for one last championship run, and fans are hoping to see the talented signal-caller add one more ring before calling it a career.